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Personal Reviews

Berg, P., 2003. Moments of Discovery: My Favorite Experiments. J.Biol.Chem. 278: 40417-24
Berg, P. 2008. Moments of discovery Annual Review of Biochemistry 77: 15-44
Berg, P. 1981. Nobel Prize paper Dissections and Reconstructions of Genes and Chromosomes Science 213: 246

Public Policy papers

• Berg, P., Baltimore, D., Boyer, H., Cohen, S., Davis, R., Hogness, D., Nathans, D., Roblin, R.,
  Watson, J., Weissman, S.,
• Zinder, N. 1974. Potential biohazards of recombinant DNA molecules. Science 185: 303.
  Berg, P., Baltimore, D., Brenner, S., Roblin, RO., Singer, M. 1975. Asilomar conference on
  recombinant DNA molecules. Science 188: 991.
• Berg, P., Singer, M. 1995. The recombinant DNA controversy: Twenty years later. PNAS 92,
• Berg, P., 2004. Asilomar and Recombinant DNA. website: http://www.nobel.se/chemistry/articles   (August 26, 2004)
• Berg, P., 1999. "Scientists and the Public: An Ambivalent Partnership" Useful Knowledge, Amer.
  Phil. Soc. 1999; 71-78:
• Berg, P, 2006. Brilliant Science, Dark Politics, Uncertain Law. Jurimetrics 46
• Berg P, 2006. Origins of the human genome project: why sequence the human genome when
  96% of it is junk? Am. J. Hum. Genet. 79: 4: 603-5


• Singer, M., Berg, P. 1990. Genes and Genomes: A Changing Perspective. Mill Valley (CA)
  University Science Books
• Berg, P., Singer, M. 1992. Dealing with Genes: The Language of Heredity. Mill Valley (CA):
  University Science Books
• Singer, M., Berg, P. 1997. Exploring Genetic Mechanisms. Sausalito, University Science Books.
  Berg, P, Singer, M. 2003 George Beadle: An Uncommon Farmer. Cold Spring Harbor Laboratory
  Press (NY)


Significant Publications from the BERG LAB
1.   Chamberlin, M. Berg, P. 1962. Deoxyribonucleic acid-directed synthesis of ribonucleic acid by an enzyme from Escherichia coli. PNAS 48: 81.
2.   Wood, WB. Berg, P. 1962. The effect of enzymatically synthesized ribonucleic acid on amino acid incorporation by a soluble protein-ribosome system from Escherichia coli..
PNAS 48: 94.
3.   Norris, AT., Berg P. 1964. Baldwin, AN., Berg, P. 1966/ Purification and properties of isoleucyl ribonucleic acid synthetase from E. coli. J. Biol. Chem. 241: 831. Mechanism
of aminoacytl RNA synthesis: Studies with isolated aminoacyl adenylate complexes of
isoleucyl RNA synthetase. PNAS 52: 330.
4.   Carbon, J., Berg, P., Yanofsky, C. 1966. Missense suppression due to a genetically
altered tRNA. Cold Spring Harbor Symp. 31: 487.
5.   Soll, L., Berg, P. 1969. Recessive lethals: A new class of nonsense suppressors in Escherichia coli . PNAS 63: 392. Soll, L., Berg, P. 1969 Recessive lethal nonsense
suppressor in Escherichia coli, which inserts glutamine. Nature 233: 1340.
6.   Jackson, DA., Symons, RH., Berg, P. 1972. Biochemical method for inserting new
genetic information into DNA of Simian Virus 40: Circular SV40 DNA molecules
containing lambda phage genes and the galactose operon of Escherichia coli.
PNAS 69: 2904.
7.   Mertz, J., Carbon, J., Herzberg, M., Davis, R., Berg, P. 1974. Isolation and characteri-
zation of individual clones of Simian Virus 40 mutants containing deletions, duplications
and insertions in their DNA. Cold Spring Harbor Symp. Quant. Biol. 39: 69 and in Viral
Transformation and Endogenous Viruses (Kaplan, A.S., Ed.). New York:
Academic Press
8.   Carbon, J., Shenk, TE., Berg, P. 1975. Biochemical procedure for production of small deletions in simian virus 40 DNA. PNAS 72: 1392. Shenk, TE., Carbon, J., Berg, P.
1976. Construction and analysis of viable deletion mutants of simian virus 40.
J. Virol. 18: 664.
9.   Mulligan, RC., Howard, BH. , Berg, P. 1979 Synthesis of rabbit b-globin recombinant genome. Nature 277, 108-114.
10.   Goff, SP, Berg, P. 1979. Construction, propagation and expression of simian virus
40 recombinant genomes containing the Escherichia coli gene for thymidine kinase and
a Saccharomyces cerevisae gene for tyrosine transfer RNA. J. Mol. Biol. 133, 359.
11.   Mulligan, RC. , Berg, P. 1980. Expression of a bacterial gene in mammalian cells.
Science 209, 1422-1427.
Mulligan, RC. , Berg, P. 1981. Selection for animal cells that
express the Escherichia coli gene coding for xanthine-guanine phosphoribosyl
transferase. PNAS 78, 2072-2076.
12.   Okayama, H., Berg, P. 1982. High efficiency cloning of full-length cDNA. Molec. and
Cell. Biol. 2, 161-170.
Okayama, H., Berg, P. 1983. A cDNA-cloning vector that permits
expression of cDNA inserts in mammalian cells. Mol. & Cell. Biol. 3, 2, 280-289.
13.   13. Fromm, M., Berg, P. 1983. SV40 early and late region promoter function are
enhanced by the 72 base pair repeat inserted at distant locations and inverted
orientations. Mol. and Cell. Biol. 3, 991-999.
14.   14. Jessberger, R., Berg, P.1991. Repair of deletions and double strand gaps by
homologous recombination in a mammalian in vitro system. Molec. and Cell. Biol.
11: 445-457.
15.   15. Donoho, G., Jasin, M., Berg, P.1998. Analysis of gene targeting and
intrachromosomal homologous recombination stimulated by genomic double-strand
breaks in mouse embryonic stem cells. Molec & Cell Biology 18: 4070.
Personal story
About Paul Berg (Bio)

Protein Synthesis film

P. Berg & Nate Oliveira film

Web site for Berg description of first recombinant DNA

Paul Berg on Science Policy